The FY22 Defense Appropriations Act provides funding for the Hearing Restoration Research Program (HRRP) to support innovative and impactful research that pursues the treatment of auditory system injuries and the restoration of hearing.  The managing agent for the anticipated funding opportunities is the CDMRP at the U.S. Army Medical Research and Development Command (USAMRDC).

 

The FY22 HRRP funding opportunity announcements for the following award mechanisms is posted on the Grants.gov website. 

 

Applications submitted to the FY22 HRRP must address one or more of the following Focus Areas:

 

• Accelerate translation of biological regeneration/repair mechanisms into therapies that treat auditory system injury and restore auditory function.  For example, but not limited to:

• ○       Hair cell regeneration/repair/recovery
• ○       Neural regeneration/repair/recovery
• ○       Treatment for synaptopathy and hidden hearing loss

• Diagnostic tests that help differentiate sensory, neural, synaptic, and central processing disorders, that may inform applicability and outcomes for current or future hearing restoration therapeutics.
• Develop reliable in-vitro human models to facilitate the understanding, derivation and characterization of human auditory cells, and/or to facilitate the evaluation of hearing restoration therapies.
• Develop and/or validate techniques/methods beyond the audiogram to diagnose acute auditory system injury in austere or remote environments.  For example, but not limited to, simple and rapid assessments that are compatible with portable platforms.

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• Funding Opportunities-FY22 HRRP, Congressionally Directed Medical Research Programs (CDMRP), US DoD (army.mil)
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• Focused Research Award – Preproposal due July 22, 2022
• Independent investigators at all academic levels (or equivalent) are eligible to submit applications.
• ·    Pre-application submission is required; application submission is by invitation only.
• ·    Supports promising research that will accelerate drug discovery and therapeutic development for hearing restoration or accelerate advances in the assessment, diagnostics, and treatment of auditory dysfunction.

·    Research must address one or more of the FY22 HRRP Focus Areas.

·    Funding Level 1 supports exploratory, high-risk/high-reward research that is in the earliest stages of idea development.

·    Funding Level 2 supports the advancement of more mature research toward clinical translation.

·    Funding Level 3 supports research with a translational research component and a related pilot clinical trial component.

·    It is the responsibility of the applicant to select the funding level that is most appropriate for the research proposed.  The funding level should be selected based on the stage and maturity of the research, rather than the amount of the budget.

·    Tinnitus or vestibular-related research is excluded.

Funding Level 1:

·    Maximum funding of $250,000 for direct costs (plus indirect costs).

·    Maximum period of performance is 2 years.

Funding Level 2:

·    Maximum funding of $1,000,000 for direct costs (plus indirect costs).

·    Maximum period of performance is 3 years.

Funding Level 3:

·    Maximum funding of $1,250,000 for direct costs (plus indirect costs).

·    Maximum period of performance is 3 years.

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A pre-application is required and must be submitted through the electronic Biomedical Research Application Portal (eBRAP) at https://eBRAP.org prior to the pre-application deadline.  All applications must conform to the final funding opportunity announcements available for downloading from the Grants.gov website.  The application package containing the required forms for each award mechanism will also be found on Grants.gov.  A listing of all CDMRP and other USAMRDC extramural funding opportunities can be obtained on the Grants.gov website by performing a basic search using CFDA Number 12.420.

 

For email notification when announcements are released, subscribe to program-specific news and updates under “Email Subscriptions” on the eBRAP homepage at https://eBRAP.org.  For more information about the HRRP or other CDMRP-administered programs, please visit the CDMRP website (https://cdmrp.army.mil).

 

Point of Contact:

CDMRP Help Desk
301-682-5507
help@eBrap.org